OUTLINE

•LEARNING OBJECTIVES

•INTRODUCTION

•NEUROTRANSMITTERS AND THEIR RECEPTORS

•CONCLUSION

• REFERENCES

LEARNING OBJECTIVES

•Describe synthesis, storage, release, reuptake and degradation of major neurotransmitters.

•Define neurotransmitters and receptors and explain their role in chemical communication.

•Review major monoamine, cholinergic and amino-acid neurotransmitter systems. Relate neurotransmitters and receptors to important neuropsychiatric disorders and drug actions

NEUROTRANSMITTER

•A chemical messenger released by a neuron that alters the activity of another cell through specific receptors.

•A typical neurotransmitter generally have mechanisms for synthesis, storage and release.

•The physiological effect depends on the receptor subtype and the target cell

•Neurotransmitters influence cognition, emotion, movement, arousal, sleep, motivation and autonomic functions.

•A single behavioral process is usually influenced by several interacting neurotransmitters.

•Receptor diversity allows the same nerotransmitter to produce different effects in different cells