
OUTLINE
Definition
Epidemiology
Classification
Pathogenesis
Clinical features
Investigations
Diagnosis
Complications
Treatment
DIABETES MELLITUS – Definition
Group of metabolic disorders characterized by:
◦Hyperglycaemia due to
◦Deficiencies of Insulin action and/or secretion leading to
◦Disturbances in metabolism of:
Carbohydrate
Fat
Protein
Associated with long term damage, dysfunction and failure of various organs: Eyes, Kidneys, Nerves, Heart & blood vessels
In other words, failure of insulin secretion, action or both lead(s) to rise in blood glucose and other metabolic changes, which if uncorrected cause complications.